- 专利标题： PROTEINS OF THE WNT SIGNALING PATHWAY AND USES THEREOF IN THE DIAGNOSTIC AND TREATMENT OF HYPOPIGMENTATION DISORDERS
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申请号： US15536332申请日： 2015-12-16
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公开(公告)号： US20180180631A1公开(公告)日： 2018-06-28
- 发明人: Thierry PASSERON , Florence JOLY
- 申请人： INSERM (INSTITUTE NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE , UNIVERSITE DE NICE SOPHIA ANTIPOLIS , CHU DE NICE
- 优先权： EP14307089.4 20141218
- 国际申请： PCT/EP2015/080066 WO 20151216
- 主分类号： G01N33/68
- IPC分类号： G01N33/68 ; A61K31/506 ; A61K33/14 ; C12Q1/68 ; G01N33/50 ; A61K31/422
摘要：
The present invention relates to the identification of proteins of the WNT signaling pathway as therapeutic targets of pigmentation disorder and as biomarkers of pigmentation status. The invention in particular relates to products and methods for treating a hypopigmentation disorder. The invention also relates to products and methods for detecting, diagnosing, staging or monitoring the course of hypopigmentation disorder and is particularly suited for human subjects.
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