- 专利标题: COMPOSITION CONTAINING PALMULTANG EXTRACT FOR PROMOTING PROLIFERATION OF STEM CELLS DERIVED FROM BONE MARROW
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申请号: US15854613申请日: 2017-12-26
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公开(公告)号: US20180185447A1公开(公告)日: 2018-07-05
- 发明人: Chang Hyeong LEE , Sang Gyung KIM , Im Hee SHIN , Seung Mo KIM , Joon Seok BYUN , Ki Cheul SOHN , Sae Kwang KU
- 申请人: COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE
- 申请人地址: KR Daegu
- 专利权人: COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE
- 当前专利权人: COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE
- 当前专利权人地址: KR Daegu
- 优先权: KR10-2013-0050323 20130503
- 主分类号: A61K38/19
- IPC分类号: A61K38/19 ; A61K36/07 ; A61K36/65 ; A61K36/484 ; A61K36/284 ; A61K36/258 ; A61K36/234 ; A61K36/232 ; A61K36/076 ; A61K36/804 ; C12N5/0789 ; A61K36/64
摘要:
The present invention relates to a composition for promoting the proliferation of stem cells derived from bone marrow using a palmultang extract, and specifically, to a composition for promoting the proliferation of stem cells derived from bone marrow by administering a granulocyte colony-stimulating factor to a subject and then administering the palmultang extract to the subject. The composition of the present invention remarkably reduces side effects, such as enlargement of the spleen, which are caused by the administration of G-CSF alone for proliferation and differentiation of the stem cells, through administration in combination with the palmultang extract, thereby further promoting the proliferation and differentiation of stem cells.