The present disclosure relates to a method for manufacturing a display panel, a display panel and a display apparatus. There is provided a method for manufacturing a display panel, wherein the display panel includes a first substrate, the manufacturing method including forming a first orientation layer on a first substrate, wherein the first orientation layer includes a peripheral portion on a bezel region of the first substrate and a central portion on an active region of the first substrate surrounded by the bezel region, and treating the peripheral portion of the first orientation layer to remove active functional groups in the material of the peripheral portion.