Invention Application
- Patent Title: CONSTRUCTS TARGETING AFP PEPTIDE/MHC COMPLEXES AND USES THEREOF
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Application No.: US15563912Application Date: 2016-04-01
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Publication No.: US20180208658A1Publication Date: 2018-07-26
- Inventor: Cheng LIU , Hong LIU , Yiyang XU , Jingyi XIANG , Li LONG
- Applicant: EUREKA THERAPEUTICS, INC.
- International Application: PCT/US16/25755 WO 20160401
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395 ; C07K14/725 ; C07K14/705 ; C07K16/30

Abstract:
The present application provides constructs comprising an antibody moiety that specifically binds to a complex comprising an AFP peptide and an MHC class I protein. Also provided are methods of making and using these constructs.
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