发明申请
- 专利标题： METHODS AND PHARMACEUTICAL COMPOSITIONS FOR ENHANCING NK CELL KILLING ACTIVITIES
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申请号： US15741944申请日： 2016-07-07
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公开(公告)号： US20180214550A1公开(公告)日： 2018-08-02
- 发明人: Armand BENSUSSAN , Martine BAGOT , Jérôme GIUSTINIANI , Yacine MERROUCHE , Adèle DE MASSON , Anne MARIE-CARDINE
- 申请人： INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , UNIVERSITÉ PARIS DIDEROT - PARIS 7 , ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP) , INSTITUT JEAN GODINOT
- 优先权： EP15306109.8 20150707
- 国际申请： PCT/EP2016/066099 WO 20160707
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61K39/39 ; C07K16/28
摘要：
The present disclosure relates to methods and pharmaceutical compositions for enhancing NK cell killing activities. In particular, the disclosure relates to a method of enhancing NK cell killing activities in a subject in need thereof comprising administering to the subject a therapeutically effective amount of a compound capable of stimulating CD245 on NK cells.
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