- 专利标题: Antipsychotic Injectable Depot Composition
-
申请号: US15944894申请日: 2018-04-04
-
公开(公告)号: US20180221272A1公开(公告)日: 2018-08-09
- 发明人: Ibon GUTIERRO ADURIZ , Maria Teresa GOMEZ OCHOA
- 申请人: LABORATORIOS FARMACEUTICOS ROVI S.A.
- 申请人地址: ES MADRID
- 专利权人: LABORATORIOS FARMACEUTICOS ROVI S.A.
- 当前专利权人: LABORATORIOS FARMACEUTICOS ROVI S.A.
- 当前专利权人地址: ES MADRID
- 优先权: EP10382154.2 20100531
- 主分类号: A61K9/00
- IPC分类号: A61K9/00 ; A61K31/519 ; A61K47/34
摘要:
The present invention is directed to a composition that can be used to deliver an antipsychotic drug such as risperidone as an injectable in-situ forming biodegradable implant for extended release providing therapeutic plasma levels from the first day. The composition is in the form of drug suspension on a biodegradable and biocompatible copolymer or copolymers solution using water miscible solvents that is administered in liquid form. Once the composition contacts the body fluids, the polymer matrix hardens retaining the drug, forming a solid or semisolid implant that releases the drug in a continuous manner. Therapeutic plasma levels of the drug can be achieved since the first day up to at least 14 days or more even up to at least four weeks.
公开/授权文献
- US10182982B2 Antipsychotic injectable depot composition 公开/授权日:2019-01-22
信息查询