In the field of radioimmunoguided surgical system instrumentation there is described and claimed a hand-held probe with a disposable power source as well as a visually perceptible indicator of detected counts of radiation. Also disclosed is a system comprising the hand-held probe and an instrumentation console. The handle includes a probe link that transmits a message containing gamma data relating to the low-level electrical signal. The instrumentation console may include a housing, a console link to receive the message transmitted by the probe link, a receiver electrically coupled to the console link to convert the message to corresponding electrical display signals, and a visually perceivable display electrically coupled to the receiver to convert the electrical display signals to a visually perceivable display relating to the amount of radiation detected.