A full-servo multi-axis die-casting machine includes an injection device body, a gooseneck operation device body and a plurality of mold locking device bodies. The injection device body includes a hollow first frame, a first servomotor, a screw, a transmission unit and an injection unit, so that the screw is caused to rotate by the first servomotor and is converted by the transmission unit into vertical reciprocal movement. The gooseneck operation device body includes a second servomotor, a first transmission arm and a second transmission arm, so that the first transmission arm and the second transmission arm are driven by the second servomotor to allow bifurcation sections to oscillate with rotation of the transmission section. The mold locking device bodies each include a third servomotor, a third transmission arm and a mold retention slide block, so that the mold retention slide block is reciprocally movable in the channel.