Provided are an antenna structure, driving method thereof, and antenna system. The antenna structure includes a first base substrate, a second base substrate, a dielectric layer disposed between the first base substrate and the second base substrate, a plurality of first electrodes, and a plurality of second electrodes. The plurality of first electrodes are disposed apart at a side of the first base substrate facing to the dielectric layer, the plurality of second electrodes are disposed apart at a side of the second base substrate facing to the dielectric layer. The first base substrate includes a plurality of first micro-hole units, each of the first micro-hole units is disposed in a region between the adjacent first electrodes, each of the first micro-hole units includes at least one micro-hole extending a direction perpendicular to the first base substrate.