Invention Application
- Patent Title: MODULATION OF AAV VECTOR TRANSGENE EXPRESSION
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Application No.: US15567847Application Date: 2016-04-20
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Publication No.: US20180311290A1Publication Date: 2018-11-01
- Inventor: Miguel Sena-Esteves , Cara Weismann , Diane Golebiowski , Lorelei Stoica
- Applicant: University of Massachusetts
- Applicant Address: US MA Boston
- Assignee: University of Massachusetts
- Current Assignee: University of Massachusetts
- Current Assignee Address: US MA Boston
- International Application: PCT/US2016/028367 WO 20160420
- Main IPC: A61K35/761
- IPC: A61K35/761 ; C12N9/38 ; A61K48/00 ; A61P25/28 ; C12N15/861 ; A61P43/00
Abstract:
Aspects of the invention relate to recombinant adeno-associated viruses (rAAVs). In some aspects, the rAAVs comprise artificial genetic regulatory elements that modulate transgene expression. In some aspects, the disclosure relates to the treatment of lysosomal storage disorders.
Public/Granted literature
- US11020443B2 Modulation of AAV vector transgene expression Public/Granted day:2021-06-01
Information query
