Invention Application
- Patent Title: PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS
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Application No.: US15874163Application Date: 2018-01-18
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Publication No.: US20180339988A1Publication Date: 2018-11-29
- Inventor: Stephanos Ioannidis , Adam Charles Talbot , Bruce Follows , Alexandre Joseph Buckmelter , Minghua Wang , Ann-Marie Campbell , Darby Rye Schmidt , David Joseph Guerin , Justin Andrew Caravella , R. Bruce Diebold , Anna Ericsson , David R. Lancia, JR.
- Applicant: FORMA Therapeutics, Inc.
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; C07D519/00
Abstract:
The invention relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula: where m, n, X1, X2, R1-R5, R5 and R6 are described herein.
Public/Granted literature
- US10377760B2 Pyrrolo and pyrazolopyrimidines as ubiquitin-specific protease 7 inhibitors Public/Granted day:2019-08-13
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