- 专利标题： METHODS AND ANTIBODIES FOR MODULATION OF IMMUNORESPONSE
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申请号： US15735912申请日： 2016-06-12
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公开(公告)号： US20180362651A1公开(公告)日： 2018-12-20
- 发明人: Yen-Ta LU , Chia-Ming CHANG , Tsai-Yin WEI , I-Fang TSAI , Ling-Chiao WU
- 申请人： Mackay Medical Foundation The Presbyterian Church In Taiwan Mackay Memorial Hospital
- 申请人地址： TW Taipei
- 专利权人： Mackay Medical Foundation The Presbyterian Church In Taiwan Mackay Memorial Hospital
- 当前专利权人： Mackay Medical Foundation The Presbyterian Church In Taiwan Mackay Memorial Hospital
- 当前专利权人地址： TW Taipei
- 国际申请： PCT/CN2016/085451 WO 20160612
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; A61K45/06 ; A61K39/395
摘要：
A method fits reversing immune suppression or immune exhaustion or for treating a disease associated with immune suppression includes: administering a co position to a subject in need of such treatments wherein the composition contains a CD11b modulator that binds specifically to CD11b on a cell to inhibit PD-L1 expression. The CD11b modulator is an antibody or an antigen-binding portion thereof, or a compound as described.
公开/授权文献
- US11685785B2 Methods and antibodies for modulation of immunoresponse 公开/授权日：2023-06-27
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