A touch display module, a manufacturing method thereof and a display device are provided. The touch display module includes a display panel and a touch module attached to the display panel; the touch module includes a touch region provided with a touch electrode and a border region provided with a black matrix, and the touch module includes a base substrate and includes a first anti-shadow layer and a second anti-shadow layer which are at a side, close to the display panel, of the base substrate; the first anti-shadow layer is between the touch electrode and the base substrate; the second anti-shadow layer is at a side, away from the base substrate, of the touch electrode; and in a dark state display mode, a color difference between the touch region and the border region is smaller than a preset value.