A profiled display panel and a display device are provided. A display region of the profiled display panel has a profiled border. The profiled display panel includes a plurality of pixels including low-brightness pixels and regular pixels. Brightness of the low-brightness pixels is lower than brightness of the regular pixels under same driving voltage. The plurality of pixels forms a plurality of pixel rows extending in first direction and a plurality of pixel columns extending in second direction. Each of the pixel rows or the pixel columns includes at least one pixel group including the low-brightness pixels at one end of the pixel group and the regular pixels at the other end, and the regular pixels are arranged away from the profiled border. An aperture area of the respective low-brightness pixels in same pixel group is gradually increased in direction from the profiled border to the display region.