- 专利标题: FGF21 Mutants and Uses Thereof
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申请号: US15996232申请日: 2018-06-01
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公开(公告)号: US20190023757A1公开(公告)日: 2019-01-24
- 发明人: Edward John Belouski , Murielle Marie Ellison , Agnes Eva Hamburger , Randy Ira Hecht , Yue-Sheng Li , Mark Leo Michaels , Jeonghoon Sun , Jing Xu
- 申请人: AMGEN INC.
- 主分类号: C07K14/50
- IPC分类号: C07K14/50 ; A61K38/18 ; C07K16/18 ; A61K38/00 ; A61K39/00
摘要:
The invention provides nucleic acid molecules encoding FGF21 mutant polypeptides, FGF21 mutant polypeptides, pharmaceutical compositions comprising FGF21 mutant polypeptides, and methods for treating metabolic disorders using such nucleic acids, polypeptides, or pharmaceutical compositions.
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