- 专利标题： NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS
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申请号： US15959935申请日： 2018-04-23
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公开(公告)号： US20190084947A1公开(公告)日： 2019-03-21
- 发明人: Edward Roberts , Hugh Rosen , Steven Brown , Miguel A. Guerrero , Xuemei Peng , Ramulu Poddutoori
- 申请人： The Scripps Research Institute
- 主分类号： C07D271/06
- IPC分类号： C07D271/06 ; C07D413/14 ; A61K31/4245 ; C07D413/04 ; C07D471/04 ; C07D263/32 ; C07D401/04
摘要：
Compounds that activate a sphingosine-1-phosphate receptor of the subtype 1 are provided. Certain compounds selectively activate the receptor subtype 1 in relation to the sphinogosine-1-phosphate receptor subtype 3. Uses and methods of inventive compounds for treatment of malconditions wherein activation, agonism, inhibition or antagonism of the S1P1 is medically indicated are provided.
公开/授权文献
- US10544136B2 Modulators of sphingosine phosphate receptors 公开/授权日：2020-01-28
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