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发明申请
US20190084948A1 Efficient and scalable synthesis of 2-(1'H-Indole-3'-Carbonyl)-thiazole-4-carboxylic acid methyl ester and its structural analogs 审中-公开

  • 专利标题： Efficient and scalable synthesis of 2-(1'H-Indole-3'-Carbonyl)-thiazole-4-carboxylic acid methyl ester and its structural analogs
  • 申请号： US15998528
    申请日： 2018-08-16
  • 公开(公告)号： US20190084948A1
    公开(公告)日： 2019-03-21
  • 发明人: Jiasheng Song , Suoming Zhang , Guodong Li , Luqing Yang
  • 申请人： Ariagen, Inc.
  • 申请人地址： US CA Menlo Park
  • 专利权人： Ariagen, Inc.
  • 当前专利权人： Ariagen, Inc.
  • 当前专利权人地址： US CA Menlo Park
  • 主分类号： C07D277/20
  • IPC分类号： C07D277/20
Efficient and scalable synthesis of 2-(1'H-Indole-3'-Carbonyl)-thiazole-4-carboxylic acid methyl ester and its structural analogs
摘要：
Methods of synthesizing 2−(1′H-indole-3′-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE) and structural analogs thereof. The methods include condensation reactions or condensation and oxidation reactions to form the thiazoline or thiazole moiety of ITE or its structural analogs.
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