Invention Application
- Patent Title: DIRECT PALLADIUM-CATALYZED AROMATIC FLUORINATION
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Application No.: US16083160Application Date: 2017-03-09
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Publication No.: US20190099748A1Publication Date: 2019-04-04
- Inventor: Tobias Ritter , Jeffrey Garber , Kumiko Yamamoto
- Applicant: President and Fellows of Harvard College , Studiengesellschaft Kohle mbH
- Applicant Address: US MA Cambridge DE Mülheim An Der Ruhr
- Assignee: President and Fellows of Harvard College,Studiengesellschaft Kohle mbH
- Current Assignee: President and Fellows of Harvard College,Studiengesellschaft Kohle mbH
- Current Assignee Address: US MA Cambridge DE Mülheim An Der Ruhr
- International Application: PCT/US17/21563 WO 20170309
- Main IPC: B01J31/30
- IPC: B01J31/30 ; B01J31/18 ; C07C23/10 ; C07C17/12

Abstract:
Provided herein are palladium complexes comprising a ligand of Formula (A′) and a ligand of Formula (B), wherein R1-R18 are as defined herein. The palladium complexes are useful in methods of fluorinating aryl and heteroaryl substrates. Further provided are compositions and kits comprising the palladium complexes.
Public/Granted literature
- US11179710B2 Direct palladium-catalyzed aromatic fluorination Public/Granted day:2021-11-23
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