An implantable interbody negative pressure device that permits reduced or negative pressure therapies to be applied to a portion of a patient's body. More specifically, the implantable interbody negative pressure device comprises a body portion having a plurality of openings in fluid communication with both an internal passageway and a vacuum source, and that serves as a manifold and permits reduced or negative pressure therapy to be applied to a surgical site, such as a wound or damaged bone. The application of the reduced or negative pressure to the body improves circulation and the disposal of cellular waste, and promotes bone growth and healing.