- 专利标题: NOVEL VEHICLES FOR THE TRANSFECTION OF miRNAS
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申请号: US16091071申请日: 2017-04-04
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公开(公告)号: US20190111002A1公开(公告)日: 2019-04-18
- 发明人: Alejandro SÁNCHEZ BARREIRO , Inés FERNÁNDEZ PIÑEIRO , Iker BADIOLA , Joana MÁRQUEZ
- 申请人: UNIVERSIDADE DE SANTIAGO DE COMPOSTELA , UNIVERSIDAD DEL PAIS VASCO - EUSKAL HERRIKO UNIBERTSITATEA (UPV/EHU)
- 申请人地址: ES Santiago de Compostela La Coruña
- 专利权人: UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
- 当前专利权人: UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
- 当前专利权人地址: ES Santiago de Compostela La Coruña
- 优先权: ESP201630417 20160405
- 国际申请: PCT/ES2017/070205 WO 20170404
- 主分类号: A61K9/51
- IPC分类号: A61K9/51 ; A61K31/7105
摘要:
The invention relates to a nanoparticle comprising: (i) between 60 wt.-% and 99 wt.-% sorbitan ester, relative to the total weight of the nanoparticle; (ii) a positively charged substance; and (iii) a miRNA. The invention also relates to the methods for producing same and to the uses thereof, particularly for therapeutic uses, such as cancer treatment.
公开/授权文献
- US10888529B2 Vehicles for the transfection of miRNAs 公开/授权日:2021-01-12
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