Invention Application
- Patent Title: DLL4-expressing cells and vaccine using the same
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Application No.: US16095986Application Date: 2017-04-26
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Publication No.: US20190134169A1Publication Date: 2019-05-09
- Inventor: Yi Zhang , Lijun Meng , Shan He
- Applicant: Temple University-Of The Commonwealth System of Higher Education
- Applicant Address: US PA Philadeiphia
- Assignee: Temple University-Of The Commonwealth System of Higher Education
- Current Assignee: Temple University-Of The Commonwealth System of Higher Education
- Current Assignee Address: US PA Philadeiphia
- International Application: PCT/US17/29601 WO 20170426
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61P37/06 ; A61P35/00 ; A61K39/02 ; A61K39/12

Abstract:
Methods are provided for generating DLL4-expressing immune cells. The invention also includes cellular compositions of dendritic and T cells produced by these methods. The immune cells of the invention can be used widely as components in many diagnostic and therapeutic systems, including improved vaccines to reduce the risk of graft versus host disease.
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