An active engine mounting device is provided. The active engine mounting device includes upper and lower liquid chambers partitioned by a valve unit and adjusts a vibration and a load input from an engine in response to a driving condition while a fluid passes through the valve unit and attenuates the vibration and the load. The active engine mounting device includes an insulator that encloses a core integrally formed with a mounting bolt and elastically deformed based on the load applied to the core. A main case is disposed at a circumference of a lower end portion of the insulator. A diaphragm is disposed under the main case. The valve unit is configured to selectively pass the fluid through three channels based on operation of the valve. An actuator is disposed through an auxiliary case to drive the valve in an axial direction.