发明申请
- 专利标题: ANTI-NOTCH3 ANTIBODY
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申请号: US16097489申请日: 2017-04-28
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公开(公告)号: US20190144537A1公开(公告)日: 2019-05-16
- 发明人: Heidi Okamura , William M. Winston, Jr. , Laura Poling , Alisa C. Bell
- 申请人: AVEO Pharmaceuticals, Inc.
- 国际申请: PCT/US2017/030156 WO 20170428
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; A61P35/00
摘要:
Monoclonal antibodies that bind and inhibit activation of human Notch3 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation and/or overexpression of Notch3.
公开/授权文献
- US11142573B2 Anti-Notch3 antibody 公开/授权日:2021-10-12
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