- 专利标题： MULTIPLE-COMPONENT SOLID PHASES CONTAINING AT LEAST ONE ACTIVE PHARMACEUTICAL INGREDIENT
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申请号： US16270981申请日： 2019-02-08
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公开(公告)号： US20190169130A1公开(公告)日： 2019-06-06
- 发明人: Michael J. Zaworotko , Nair Rodriguez-Hornedo , Brian Moulton
- 申请人： University of South Florida , The Regents of the University of Michigan
- 主分类号： C07D223/26
- IPC分类号： C07D223/26 ; C07C53/08 ; A61K9/16 ; C07C57/30 ; C07C57/58 ; C07C61/135 ; C07C63/307 ; C07C69/157 ; C07C205/57 ; C07C233/03 ; C07C233/75 ; C07C317/04 ; C07D213/06 ; C07D213/22 ; C07D275/06 ; C07D213/79 ; C07D213/69 ; C07D213/82 ; C07C47/544 ; C07C53/02 ; C07D233/74 ; C07C233/25 ; C07C51/43 ; C07C51/41 ; A61K47/32 ; A61K47/10 ; A61K31/616 ; A61K31/55 ; A61K31/4166 ; A61K31/192 ; A61K31/167 ; C07C53/124
摘要：
The subject invention concerns a method for identifying complementary chemical functionalities to form a desired supramolecular synthon. The subject invention also pertains to multiple-component phase compositions comprising one or more pharmaceutical entities and methods for producing such compositions.