In-band full-duplex (IBFD) wireless systems offer the ability to revolutionize frequency spectrum utilization for future networks. For IBFD systems to work, the self-interference (SI) generated by each wireless node should be sufficiently mitigated, which becomes more challenging as the bandwidth increases. RF cancellation enables this interference reduction but has been limited so far to narrowband operation or restricted to distinctive environments. Fortunately, a photonic-enabled RF canceller can provide broadband interference cancellation using photonic components in a wideband vector modulator architecture with tunable time-delay taps. An example of this canceller with 20 canceller taps provides 25 and 20 dB of cancellation over 500-MHz and 1-GHz instantaneous bandwidths, respectively, and is tunable between 0.5 and 5.5 GHz. This photonic-enabled RF canceller provides the wideband operation and high tap counts for successfully deploying future wireless systems with IBFD technology.