- 专利标题： PROTAC ANTIBODY CONJUGATES AND METHODS OF USE
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申请号： US16194897申请日： 2018-11-19
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公开(公告)号： US20190175612A1公开(公告)日： 2019-06-13
- 发明人: Thomas Pillow , Jack Sadowsky , Leanna Staben , Steven Staben , Binqing Wei , Ingrid Wertz , Pragya Adhikari , Nicole Blaquiere , Peter Dragovich , Wayne Fairbrother
- 申请人： Genentech, Inc.
- 主分类号： A61K31/551
- IPC分类号： A61K31/551 ; A61P35/00 ; A61P37/06 ; A61K47/65 ; C12N9/00 ; C07K16/32 ; C07K16/28
摘要：
The subject matter described herein is directed to antibody-PROTAC conjugates (PACs), to pharmaceutical compositions containing them, and to their use in treating diseases and conditions where targeted protein degradation is beneficial.
公开/授权文献
- US11666581B2 PROTAC antibody conjugates and methods of use 公开/授权日：2023-06-06
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