发明申请
- 专利标题： INSULIN-INCRETIN CONJUGATES
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申请号： US16083201申请日： 2017-03-13
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公开(公告)号： US20190175744A1公开(公告)日： 2019-06-13
- 发明人: Anandan Palani , Chunhui Huang , Zhiqiang Yang , Lin Yan , Songnian Lin , Pei Huo , Qiaolin Deng , Elisabetta Bianchi , Federica Orvieto
- 申请人： Anandan PALANI , Chunhui HUANG , Zhiqiang YANG , Lin YAN , Songnian LIN , Pei HUO , Qiaolin DENG , Elisabetta BIANCHI , Federica ORVIETO , Merck Sharp & Dohme Corp.
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 国际申请： PCT/US17/21999 WO 20170313
- 主分类号： A61K47/64
- IPC分类号： A61K47/64 ; A61K38/28 ; A61K38/26
摘要：
Insulin-incretin conjugates comprising a peptide having agonist activity at the glucagon-like 1 (GLP-1) receptor, the glucagon (GCG) receptor, and/or the gastric inhibitory protein (GIP) receptor conjugated to an insulin molecule having agonist activity at the insulin receptor and use of the conjugates for treatment of metabolic diseases, for example, Type 2 diabetes, are described.
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