A plug for plugging a feeding tube hub that has a male coupling defining a lumen extending therethrough, and an outer collar and an annular space defined therebetween. The plug includes a base configured for releasably covering at least a portion of an annular space defined in an outer collar of a feeding tube hub, and a plug insert extending from the base. The plug insert is configured for plugging a lumen of a feeding tube hub along a connection axis. At least one passageway extends through the base to provide access to the annular space defined in the outer collar of the feeding tube hub when the plug insert is plugging the lumen of the feeding tube hub.