A single-pass heavy-ion fusion system for power production from fusion reactions alone, power production that uses additional energy of fission reactions obtained by driving a sub-critical fission pile with the neutrons from fusion reactions, destroying high-level and/or long-lived radioactive waste by intense bombardment with fusion neutrons, or for the production of neutron beams for various applications includes a new arrangement of current multiplying processes that employs a multiplicity of isotopes to achieve the desired effect of distributing the task of amplifying the current among all the various processes, to relieve stress on any one process, and to increase the design margin for assured ICF (inertial confinement fusion) ignition for applications including but not restricted to the above list. The energy content and power of the ignition-driver pulses are greatly increased, thus increasing intensity of target heating and rendering reliable ignition readily attainable.