A device for removing circumferential burrs of a wheel with high precision includes an electric cylinder, a lifting table, guide rails, an electric cylinder, a sliding block, a plurality of sensors, a rim burr cutter, a riser burr cutter, and the like. The device can simultaneously remove circumferential burrs from the flange edge, the outer rim and the riser slot edge, which eliminates the error caused by coaxial degree deviation, so that the rotating center of the cutters coincides with the circumferential center of the burrs. The device is configured to provide high-precision removal of burrs from the flange edge, and high-precision removal of burrs from the outer rim and the riser.