Invention Application
- Patent Title: CAMK2D ANTISENSE OLIGONUCLEOTIDES AND USES THEREOF
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Application No.: US16282138Application Date: 2019-02-21
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Publication No.: US20190275148A1Publication Date: 2019-09-12
- Inventor: Richard E. Olson , Brian R. Anderson , Peter Hagedorn , Marianne Lerbech Jensen , Ivar M. McDonald , Stephen E. Mercer
- Applicant: Bristol-Myers Squibb Company , Roche Innovation Center Copenhagen A/S
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C12N5/077 ; C12N15/113 ; C12N5/074 ; A61K47/60 ; A61K47/64 ; A61K47/54 ; A61P9/04 ; A61P9/12 ; A61K9/00
Abstract:
The present disclosure relates to antisense oligonucleotides, which target CAMK2D mRNA in a cell, leading to reduced expression of CAMK2D protein. Reduction of CAMK2D protein expression is beneficial for the treatment of certain medical disorders, e.g., cardiovascular-related diseases or disorders.
Public/Granted literature
- US11058767B2 CAMK2D antisense oligonucleotides and uses thereof Public/Granted day:2021-07-13
Information query
