- 专利标题： Synthetic Oligosaccharide Subunits Of The PSL Exopolysaccharide Of Pseudomonas Aeruginosa And Uses Thereof
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申请号： US16219199申请日： 2018-12-13
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公开(公告)号： US20190309095A1公开(公告)日： 2019-10-10
- 发明人: Antonio DiGiandomenico , Qun Wang , Charles K. Stover , Geert-Jan Boons , Kai-For Mo , Huiqing Li
- 申请人： MedImmune Limited , University Of Georgia Research Foundation, Inc.
- 主分类号： C08B37/00
- IPC分类号： C08B37/00 ; A61K47/64 ; A61K39/104 ; C07H15/04 ; G01N33/569 ; G01N33/53
摘要：
This disclosure relates to synthetic oligosaccharide subunits of the Pseudomonas exosaccharide Psi and uses thereof, e.g., for epitope mapping of anti-Psl antibodies, for identification of anti-Psl antibodies, and for use as vaccines. In one aspect a synthetic oligosaccharide subunit of a Pseudomonas aeruginosa Psl oligosaccharide is provided, comprising the trisaccharide of formula I.
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