- 专利标题： Molecular Complex for Targeting Antigens Towards Cells Comprising Antigens and Uses Thereof for Vaccination
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申请号： US16502498申请日： 2019-07-03
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公开(公告)号： US20190322731A1公开(公告)日： 2019-10-24
- 发明人: Michel Leonetti , Alexandra Savatier , Adeline Gadzinski , Jean-Claude Boulain
- 申请人： Michel Leonetti , Alexandra Savatier , Adeline Gadzinski , Jean-Claude Boulain
- 申请人地址： FR Paris
- 专利权人： Commissariat a l'Energie Atomique et aux Energies Alternatives
- 当前专利权人： Commissariat a l'Energie Atomique et aux Energies Alternatives
- 当前专利权人地址： FR Paris
- 优先权： FR1000392 20100201
- 主分类号： C07K16/18
- IPC分类号： C07K16/18 ; A61K47/68 ; A61K47/64 ; C07K16/28 ; A61K39/39
摘要：
The invention relates to a molecular complex for targeting the antigen towards cells comprising antigens, including at least one antigen associated with at least two ligands of surface molecules of cells comprising antigens, said complex including at least one first ligand of a sulphated sugar of the glycosaminoglycan family and a second ligand of a specific surface molecule of cells comprising antigens, and said first ligand being covalently bonded with said antigen and/or said second ligand.
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