Invention Application
- Patent Title: PYRIMIDINONE DERIVATIVES AS CDC7 INHIBITORS
-
Application No.: US16348073Application Date: 2017-11-07
-
Publication No.: US20190336502A1Publication Date: 2019-11-07
- Inventor: Emma L. Carswell , Mark David Charles , Chukuemeka Tennyson Ekwuru , Frederic Elustondo , Katherine M. Fowler , Gregory R. Ott , Jonathan R. Roffey , Joanna L. Brookfield , Daniel James Ford , Mathew L. Calder
- Applicant: Cancer Research Technology Limited
- Priority: GB1618845.0 20161108
- International Application: PCT/GB2017/053336 WO 20171107
- Main IPC: A61K31/506
- IPC: A61K31/506 ; C07D417/14 ; A61K31/551 ; A61K31/437 ; C07D471/04 ; C07D403/14 ; C07D413/14
Abstract:
The present invention relates to compounds of formula I as defined herein, and salts and solvates thereof, that function as inhibitors of cell division cycle 7 (Cdc7) kinase enzyme activity. The present invention also relates to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which Cdc7 kinase activity is implicated.
Public/Granted literature
- US11020396B2 Pyrimidinone derivatives as Cdc7 inhibitors Public/Granted day:2021-06-01
Information query
IPC分类:
