Invention Application
![SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS](/docs/US/2019-12-05/US20190365763A1/abs.jpg.600x600.jpg)
- Patent Title: SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS
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Application No.: US16377514Application Date: 2019-04-08
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Publication No.: US20190365763A1Publication Date: 2019-12-05
- Inventor: Shelley Allen , Steven W. Andrews , Kevin Ronald Condroski , Julia Haas , Lily Huang , Yutong Jiang , Timothy Kercher , Jeongbeob Seo
- Applicant: Array BioPharma Inc.
- Main IPC: A61K31/519
- IPC: A61K31/519 ; C07D519/00 ; C07D487/04 ; C07D453/02 ; C07D471/22 ; C07D498/22 ; A61K31/5377
![SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS](/abs-image/US/2019/12/05/US20190365763A1/abs.jpg.150x150.jpg)
Abstract:
Compounds of Formula I: and salts thereof in which R1, R2, R3, R4, X, Y and n have the meanings given in the specification, are inhibitors of Trk kinases and are useful in the treatment of diseases which can be treated with a Trk kinase inhibitor such as pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases.
Public/Granted literature
- US10758542B2 Substituted pyrazolo[l,5-a]pyrimidine compounds as Trk kinase inhibitors Public/Granted day:2020-09-01
Information query
IPC分类:
