- 专利标题: NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT
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申请号: US16538208申请日: 2019-08-12
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公开(公告)号: US20190388405A1公开(公告)日: 2019-12-26
- 发明人: Kenneth W. Bair , Timm R. Baumeister , Alexandre J. Buckmelter , Karl H. Clodfelter , Peter Dragovich , Francis Gosselin , Bingsong Han , Jian Lin , Dominic J. Reynolds , Bruce Roth , Chase C. Smith , Zhongguo Wang , Po-Wai Yuen , Xiaozhang Zheng
- 申请人: Forma TM, LLC , Genentech, Inc.
- 主分类号: A61K31/4355
- IPC分类号: A61K31/4355 ; C07D491/048 ; C07D487/04 ; A61K45/06 ; A61K31/55 ; A61K31/5377 ; A61K31/519 ; A61K31/497 ; A61K31/496 ; A61K31/437 ; A61K31/4365 ; C07D495/04 ; C07D491/04 ; C07D471/04
摘要:
The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below:
公开/授权文献
- US10772874B2 Compounds and compositions for the inhibition of NAMPT 公开/授权日:2020-09-15