- 专利标题： ENGINEERED PHOSPHOPENTOMUTASE VARIANT ENZYMES
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申请号： US16460062申请日： 2019-07-02
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公开(公告)号： US20200010823A1公开(公告)日： 2020-01-09
- 发明人: Scott J. Novick , Xiang Yi , Nikki Dellas , Oscar Alvizo , Jovana Nazor , Da Duan , Vesna Mitchell , Jonathan Vroom , Santhosh Sivaramakrishnan , Nandhitha Subramanian , Jeffrey C. Moore , Mark Huffman , Agustina Rodriguez-Granillo , Deeptak Verma , Grant Murphy , Nicholas M. Marshall , Jay Russell , Keith A. Canada
- 申请人： Codexis, Inc.
- 主分类号： C12N9/90
- IPC分类号： C12N9/90 ; C12N15/52 ; C12N15/81 ; C12N15/74
摘要：
The present invention provides engineered phosphopentomutase (PPM) enzymes, polypeptides having PPM activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PPM enzymes are also provided. The present invention further provides compositions comprising the PPM enzymes and methods of using the engineered PPM enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
公开/授权文献
- US11034948B2 Engineered phosphopentomutase variant enzymes 公开/授权日：2021-06-15