![SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS](/docs/US/2020-01-30/US20200030311A1/abs.jpg.600x600.jpg)
- 专利标题： SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS
-
申请号： US16579150申请日： 2019-09-23
-
公开(公告)号： US20200030311A1公开(公告)日： 2020-01-30
- 发明人: Steven W. ANDREWS , Sean ARONOW , James F. BLAKE , Barbara J. BRANDHUBER , James COLLIER , Adam COOK , Julia HAAS , Yutong JIANG , Gabrielle R. KOLAKOWSKI , Elizabeth A. McFADDIN , Megan L. McKENNEY , Oren T. McNULTY , Andrew T. METCALF , David A. MORENO , Ginelle A. RAMANN , Tony P. TANG , Li REN , Shane M. WALLS
- 申请人： Array Biopharma Inc.
- 主分类号： A61K31/4545
- IPC分类号： A61K31/4545 ; A61K31/4162 ; C07D471/04 ; A61P1/00 ; A61P35/00 ; A61P35/02 ; A61K31/444 ; A61K31/497 ; A61K31/501 ; A61K31/506 ; A61K31/5377 ; A61K45/06 ; A61P1/12
![SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS](/abs-image/US/2020/01/30/US20200030311A1/abs.jpg.150x150.jpg)
摘要：
Provided herein are compounds of the Formula I: or pharmaceutically acceptable salt or solvate thereof, wherein A, B, X1, X2, X3, X4, Ring D, E, Ra, Rb, n and m have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.
公开/授权文献
信息查询
IPC分类:
