发明申请
- 专利标题： DERIVATIVES OF AMANITA TOXINS AND THEIR CONJUGATION TO A CELL BINDING MOLECULE
-
申请号： US16078080申请日： 2016-04-20
-
公开(公告)号： US20200079820A1公开(公告)日： 2020-03-12
- 发明人: Robert Yongxin ZHAO , Qingliang YANG , Yuanyuan HUANG , Shun GAI , Hangbo YE , Chengyu YANG , Huihui GUO , Xiaomai ZHOU , Hongsheng XIE , Qianqian TONG , Minjun CAO , Linyao ZHAO , Junxiang JIA , Wenjun LI , Xiaotao ZUO , Chen LIN , Yifang XU , Zixiang GUO
- 申请人： Hangzhou DAC Biotech Co., Ltd.
- 申请人地址： CN Hangzhou, Zhejiang
- 专利权人： Hangzhou DAC Biotech Co., Ltd.
- 当前专利权人： Hangzhou DAC Biotech Co., Ltd.
- 当前专利权人地址： CN Hangzhou, Zhejiang
- 国际申请： PCT/IB2016/052246 WO 20160420
- 主分类号： C07K7/64
- IPC分类号： C07K7/64 ; C07K16/32
摘要：
The present invention is related to novel cytotoxic agents, derivatives of Amanita toxins of Formula (I), wherein , - - - , R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, L, m, n and Q are defined herein, the preparation and the therapeutic uses in the targeted treatment of cancers, autoimmune disorders, and infectious diseases.
信息查询
