A device for removing wheel burrs with brushes not only can be used for continuous automation production, but also can correspondingly adjust the shape of the burr brushes according to the wheel model, so that the shape of the burr brushes is consistent with the shape of wheel spoke back cavity and the shape of the center cap mouth, which does not need to manufacture large quantities of different specifications of brushes, thus saving the manufacture cost. The device has high universality and application value.