Provided is a system and method for predicting leading indicators for predicting occurrence of an event at a target asset. Rather than rely on traditional manufacturer-defined leading indicators for an asset, the examples herein predict leading indicators for a target asset based on actual operating conditions at the target asset. Accordingly, unanticipated operating conditions can be considered. In one example, the method may include receiving operating data of a target resource, the operating data being associated with previous occurrences of an event at the target resource, predicting one or more leading indicators of the event at the target resource based on the received operating data, each leading indicator comprising a variable and a threshold value for the variable, and outputting information about the one or more predicted leading indicators of the target resource for display via a user interface.