Invention Application
- Patent Title: VARIANTS OF CD38 ANTIBODY AND USES THEREOF
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Application No.: US16786563Application Date: 2020-02-10
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Publication No.: US20200165352A1Publication Date: 2020-05-28
- Inventor: Bart De GOEIJ , Grietje ANDRINGA , Frank BEURSKENS , Janine SCHUURMAN , David P.E. SATIJN , Tahamtan AHMADI
- Applicant: GENMAB A/S
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61P35/00
Abstract:
Antibody variants comprising one or more mutations in the Fc region, particularly anti-CD38 antibodies comprising a mutation in one or more amino acid residues corresponding to E430, E345 and S440 in a human IgG1 heavy chain, wherein the amino acid residues are numbered according to the EU index.
Information query
