Facial skin mask generated by a digital content creation system is described. The digital content creation system includes digital effects on skin in facial regions of digital content with efficiency and accuracy. Upon identifying a facial region within digital content, the system generates a first regional skin mask, a second regional skin mask, and combines both of the first and second regional skin masks to generate a facial skin mask indicative of skin of the identified facial regions depicted in digital content. The digital content creation system then modifies digital content by applying user selected digital effects to the skin of the facial region using the generated facial skin mask.