Examples described herein relate to providing a streaming protocol packet segmentation offload request to a network interface. The request can specify a segment of content to transmit and meta data associated with the content. The offload request can cause the network interface to generate at least one header field value for the packet and insert at least one header field prior to transmission of the packet. In some examples, the network interface generates a validation value for a transport layer protocol based on the packet with the inserted at least one header field. Some examples provide for pre-packetized content to be stored and available to copy to the network interface. In such examples, the network interface can modify or update certain header fields prior to transmitting the packet.