A dialysis system (e.g., a hemodialysis (HD) system) can be designed to operate in alternative environments, such as disaster relief settings or underdeveloped regions. The dialysis system can include a solar panel for generating electricity to power the dialysis machine and an atmospheric water generator for extracting water from ambient air. The extracted water can be used to generate dialysate and saline on-site. One or more of the components of the dialysis machine can be discrete components that are configured to facilitate fast shipping and simple on-site assembly (e.g., at a remote location). In some implementations, the discrete components may be configured to be attached to an existing dialysis system (e.g., a dialysis system designed for operation in a traditional environment) to permit the dialysis system to operate in an alternative environment.