A cleaning machine for cleaning particles on a plate member includes a first cleaning device, a second cleaning device, a driving module, a spraying module and a control system. The first cleaning device is rotatable on the plate member. The second cleaning device is rotatable on the plate member. The driving module connected to the first cleaning device and the second cleaning device drives the first cleaning device and the second cleaning device to rotate at least one of the first cleaning device and the second cleaning device. The spraying module sprays liquid. The control system coupled to the spraying module and the driving module controls operations of the spraying module and the driving module. The spraying module of the cleaning machine of the invention has a wider spraying range, so that a wetted range on the plate member is wider.