A touch panel and a manufacturing method thereof, and a touch display device are provided. The touch panel includes a first substrate and a second substrate disposed opposite to each other, and the first substrate and the second substrate have an interval therebetween. The first substrate includes a first base substrate and a force touch electrode layer disposed on the first base substrate, the force touch electrode layer includes a plurality of independent force touch electrodes. The second substrate includes a second base substrate and a capacitance reference layer disposed on the second base substrate.