- 专利标题： A PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE
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申请号： US16652910申请日： 2018-10-04
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公开(公告)号： US20200317721A1公开(公告)日： 2020-10-08
- 发明人: Kleomenis BARLOS , Konstantinos BARLOS , Dimitrios GATOS , Zoi VASILEIOU
- 申请人： CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A.
- 优先权： com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@7a2eb278 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@1637a64c
- 国际申请： PCT/IB2018/057736 WO 20181004
- 主分类号： C07K1/02
- IPC分类号： C07K1/02 ; C07K14/605
摘要：
A process for preparing a GLP-1 or GLP-2 peptide, said process comprising coupling in solution at least a first fragment and at least a second fragment, wherein the coupling comprises reacting the carboxy terminal amino acid of the first fragment with the amino terminal amino acid of the second fragment, and wherein the carboxy terminal amino acid of the first fragment is other than a Gly residue