The present disclosure relates generally to stents and methods for managing passage of material through a body lumen. In some embodiments, a medical stent may include a stent body defined by a hollow tubular elongate structure extending along a central axis, the stent body including a first portion and a second portion. The medical stent may further include a control region between the first and second portions, wherein in a first configuration the hollow tubular elongate structure of the control region is in a closed, twisted configuration, and wherein in a second configuration the hollow tubular elongate structure of the control region is in an open, expanded configuration.