An ostomy collection and drainage system includes an ostomy pouch (10) having an outer wall defining an internal collection area, an inlet opening (14) formed in the outer wall in fluid communication with the internal collection area and an outlet body (20) connected to the outer wall having an outlet opening extending therethrough in fluid communication with the internal collection area, the outlet body having one of a latch and a catch. The system further includes a closure (40) configured for removable coupling to the outlet body and an adapter (60) configured for removable coupling to the outlet body, the adapter having an adapter opening extending therethrough and the other of the latch and the catch. The adapter and the closure are interchangeably coupled to the outlet body such that in a first condition the adapter is coupled to the outlet body by way of engagement of the catch and the latch, and in a second condition the closure is coupled to the outlet body.